DDI Harbors the Largest Biobank in Kuwait with over 500,000 samples
The Dasman Diabetes Biobank plays a pivotal role within the Dasman Diabetes Institute, serving as a central repository for numerous projects and initiatives. Its significance lies in its vast collect
Implementation of National Diabetes Registry in Kuwait
Diabetes is a chronic disease that requires continuous engagement with healthcare services. To establish a comprehensive profile of individuals with diabetes and monitor their clinical outcomes, incl
DDI Launches a New Study The Kuwait Adult Diabetes Epidemiological Multidisciplinary or KADEM
The KADEM study is a continuation of the Kuwait Diabetes Epidemiology Program (KDEP), which has successfully created a comprehensive research dataset on the Kuwaiti population. With a collection of c
Preterm Births have sex-specific effects on Pancreatic development and function
Preterm birth is defined as any birth that occurs before 37 weeks of gestation or in less than 259 days. In addition to contributing to mortality, preterm birth has long-term consequences, including
DDI Researchers found that Verapamil has Cytoprotective effects on Pancreatic Beta-Cella
Verapamil is a calcium channel blocker that is commonly used to treat hypertension, angina, and certain heart rhythm disorders. In this study, Dr. Fahd Al-Mulla and his team investigated the use of v
Once-weekly Exenatide in youth with Type-2 diabetes
Type 2 diabetes mellitus (T2DM) among younger individuals, which is typically more aggressive than in adults, is treated with metformin, liraglutide, and/or insulin. However, the Treatment Options fo
Early Macrophage response to obesity encompasses IRF5-regulated Mitochondrial Architecture Remodeling
Adipose tissue macrophages (ATMs) are sentinel cells that respond to microenvironmental cues. In response to chronic energy imbalance in obesity, ATMs accumulate in adipose tissue and undergo polariz
New Immunophenotypic Profiling helps identify Type 2 Diabetes (T2D) patients at risk of severe COVID-19
The Biochemistry & Molecular Biology Department at DDI published an article that investigated the effects of increased toxicity caused by palmitic acid (PA) on insulin regulation. PA, a type of f
New Immunophenotypic Profiling helps identifying T2D patients at risk of severe COVID-19
This study was a collaboration between Sorbonne Université and the Public Hospitals of Paris (Assistance Publique – Hôpitaux de Paris, AP-HP). It investigated the characteristics of immune cells in h
Can Behavioral and Environmental Factors Influence Gene Activity and Cause Type 1 Diabetes?
Recently, there has been a growing interest in examining the role of heritable changes caused by gene activation or deactivation in type 1 diabetes (T1D) development, primarily through processes
GLOBAL COLLABORATIVE APPROACH IN DISCOVERING GENETIC DETERMINANTS OF METABOLIC DISORDERS
There is currently a global effort to apply large-scale genomic science and associated technologies to further the understanding of disease pathogenesis in diverse populations. These efforts focus on
Research During 2021 in a Glance
Number and Impact factor of DDI’s published articles from 2016 until 2021. Here we highlight insightful published work in the department of Genetics and Bioinformatics: MMP9 is a molecule i
Scientists at DDI discover a new Branch in the regulation of IL-6 in Fat cells
Kuwait is amongst top-ranking nations afflicted badly by obesity epidemic and its wide-scale complications such as increased blood pressure, heart disease, stroke, digestive problems, certain cancers