2016

Khadir A, Kavalakatt S, Abubaker J, Cherian P, Madhu D, Al-Khairi I, Abu-Farha M, Warsame S, Elkum N, Dehbi M, Tiss A. Physical exercise alleviates ER stress in obese humans through reduction in the expression and release of GRP78 chaperone. Metabolism. 2016;65(9):1409-20.

Ehret GB, Ferreira T, Chasman DI, Jackson AU, Schmidt EM, Johnson T, Thorleifsson G, Luan J, Donnelly LA, Kanoni S, …Tuomilehto J, et al. The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nat Genet. 2016;48(10):1171-84.

Sindhu S, Rasheed A. Fetuin a (AHSG) in Metabolic and Inflammatory Diseases: A Foe or A Friend. Diab Obe Intl J. 2016;1(5).

Lek M, Karczewski KJ, Minikel EV, Samocha KE, Banks E, Fennell T, O'Donnell-Luria AH, Ware JS, Hill AJ, Cummings BB,… Tuomilehto J, et al. Analysis of protein-coding genetic variation in 60,706 humans. Nature. 2016;536(7616):285-91.

Giorgino F, Home PD, Tuomilehto J. Glucose Control and Vascular Outcomes in Type 2 Diabetes: Is the Picture Clear? Diabetes Care. 2016;39 Suppl 2:S187-95.

Fuchsberger C, Flannick J, Teslovich TM, Mahajan A, Agarwala V, Gaulton KJ, Ma C, Fontanillas P, Moutsianas L, McCarthy DJ, Rivas MA, …Tuomilehto J, et al. The genetic architecture of type 2 diabetes. Nature. 2016;536(7614):41-7.

Kumari M, Wang X, Lantier L, Lyubetskaya A, Eguchi J, Ahmad R, et al. IRF3 promotes adipose inflammation and insulin resistance and represses browning. J Clin Invest. 2016;126(8):2839-54.

Masoetsa R, Messenger G, Hussein I, Devarajan S, Alsaleh F, Lemay J, Veeramani M. Assessment of the evidence of the use and effectiveness of antifungals for diabetic foot ulcer infections: a systematic review. PROSPERO International prospective register of systematic reviews. 2016

Sindhu S, Al-Roub A, Koshy M, Thomas R, Ahmad R. Palmitate-Induced MMP-9 Expression in the Human Monocytic Cells is Mediated through the TLR4-MyD88 Dependent Mechanism. Cell Physiol Biochem. 2016;39(3):889-900.

Tuomilehto J, Schwarz PE. Preventing Diabetes: Early Versus Late Preventive Interventions. Diabetes Care. 2016;39 Suppl 2:S115-20.

AlSeaidan M, Al Wotayan R, Christophi CA, Al-Makhseed M, Abu Awad Y, Abraham S, et al. Birth Outcomes in a Prospective Pregnancy-Birth Cohort Study of Environmental Risk Factors in Kuwait: The TRACER Study. Paediatr Perinat Epidemiol. 2016;30(4):408-17.

Walford GA, Gustafsson S, Rybin D, Stancakova A, Chen H, Liu CT, Hong J, Jensen RA, Rice K, Morris AP… Tuomilehto J, et al. Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci. Diabetes. 2016;65(10):3200-11.

NCD Risk Factor Collaboration (NCD-RisC), Tuomilehto J. et al. A century of trends in adult human height. eLife. 2016;5.

Matz K, Seyfang L, Dachenhausen A, Teuschl Y, Tuomilehto J, Brainin M, MD for the Austrian Stroke Unit Registry Collaborators. Post-stroke pneumonia at the stroke unit - a registry based analysis of contributing and protective factors. BMC Neurol. 2016;16:107.

Cefalu WT, Buse JB, Tuomilehto J, Fleming GA, Ferrannini E, Gerstein HC, Bennett PH, Ramachandran A, Raz I, Rosenstock J, Kahn SE. Update and Next Steps for Real-World Translation of Interventions for Type 2 Diabetes Prevention: Reflections From a Diabetes Care Editors' Expert Forum. Diabetes Care. 2016;39(7):1186-201.

Hassoun AA, Pathan MF, Medlej RC, Alarouj M, Shaltout I, Chawla MS, et al. Effects of vildagliptin relative to sulfonylureas in Muslim patients with type 2 diabetes fasting during Ramadan: influence of age and treatment with/without metformin in the VIRTUE study. Diabetes Metab Syndr Obes. 2016;9:225-31.

Akhtar S, Alroughani R, Ahmed SF, Al-Hashel JY. Prognostic indicators of secondary progression in a paediatric-onset multiple sclerosis cohort in Kuwait. Mult Scler. 2016;22(8):1086-93.

Welsh P, Cezard G, Gill JM, Wallia S, Douglas A, Sheikh A, Wild SH, Tuomilehto J, McKnight J, Murray G… et al. Associations between weight change and biomarkers of cardiometabolic risk in South Asians: secondary analyses of the PODOSA trial. Int J Obes (Lond). 2016;40(6):1005-11.

Vinik AI, Smith AG, Singleton JR, Callaghan B, Freedman BI, Tuomilehto J, Bordier L, Bauduceau B, Roche F. Normative Values for Electrochemical Skin Conductances and Impact of Ethnicity on Quantitative Assessment of Sudomotor Function. Diabetes Technol Ther. 2016;18(6):391-8.

Scott LJ, Erdos MR, Huyghe JR, Welch RP, Beck AT, Wolford BN, Chines PS, Didion JP, Narisu N, Stringham HM… Tuomilehto J, et al. The genetic regulatory signature of type 2 diabetes in human skeletal muscle. Nat Commun. 2016;7:11764.