Research Achievements 2023


In 2023, the Research Sector staff of DDI presented 63 abstracts at 36 conferences (Figure 3). Researchers achieved unprecedented success in 2023 when 15 abstracts were presented at the 83rd Scientific Sessions of the American Diabetes Association (ADA). DDI researchers had the opportunity to present research from various areas currently conducted at DDI (Supplementary Table 1).

Figure 3. Breakdown of conferences attended and presented at by the Research Sector in 2023 by type.

Supplementary Table 1. List of poster and oral presentations by the Research Sector at the 83rd Scientific Sessions of the American Diabetes Association conducted on 23–26 June 2023 in San Diego, CA, USA.
All authorsPresenting AuthorDepartmentTitleType
Amal Hasan, Shihab Kochumon, Iman Albasiri, Fahd Al-Mulla, Rasheed AhmadDr. Amal HasanImmunology and MicrobiologySoluble Suppression of Tumorigenicity 2 is Directly Correlated with Body Fat, Metabolic Dysfunction, and Inflammation in Children and AdolescentsPoster
Amal Hasan, Shihab P. Kochumon, Iman D. Albasiri, Shaima Albeloushi, Ebaa S. Alozairi, Fahd AlmullaDr. Amal HasanImmunology and MicrobiologyCirculating Calprotectin is Increased in Children with T1D and Obesity: Implications for T1D Progression and OutcomePoster
Rasheed Ahmad, Texy K. Jacob, Shihab P. Kochumon, Reeby S. Thomas, Steve Shenouda, Nadeem Akhter, Ajit Wilson, Fatemah Bahman, Amal Hasan, Fatema Alrashed, Hossein Arefanian, Ashraf Al Madhoun, Fahd Almulla, Sardar T. A. K. SindhuDr. Rasheed AhmadImmunology and MicrobiologyDifferential Effects of Cocoa Butter, Sunflower, Soybean, and Fish Oil Based Sucrose-Free HFDs on Hepatic Steatosis, Lipogenesis, Inflammation, and Insulin Resistance in MicePoster
F.Al-Rashed: H.Arefanian:  S.T.Sindhu: F.Bahman: H.Alsaeed: A.Al madhoun: F.Alzaid:. F.Al-Mulla: R.Ahmad:Dr. Fatema Al-RashedImmunology and MicrobiologyNeutral Sphingomyelinase Inhibition Limits Hepatic-Lipotoxicity and Inflammation in a Cell Model of Steatosis [Board No. 1609)Poster
F.Bahman: H.Alsaeed: S.Albeloushi: F.Almulla:  R.Ahmad: F.Alrashed:Dr. Fatemah BahmanImmunology and MicrobiologyRegular Physical Activity Plays a Crucial Role in Improving the Anti-inflammatory Status of Healthy Individuals by Modulating TLR2 Expression.  Poster
Sardar Sindhu, Nadeem Akhter, Ajit Wilson, Hossein Arefanian, Reeby Thomas, Shihab Kochumon, Fatema Al-Rashed, Fatemah Bahman, Ashraf Al-Madhoun, Fawaz Alzaid, Fahd Al-Mulla, Rasheed AhmadDr. Rasheed AhmadImmunology and MicrobiologyER Stress Drives the VEGF Expression in Monocytic Cells by Mechanisms Involving CHOP/ROS/HIF-1alpha/NRF2 and NF-kappaB/p38 MAPK Pathways  Poster
Hossein Arefanian, Ashraf Al Madhoun, Fatema Alrashed, Fatemah Bahman, Halemah Alsaeed, Nermeen A. Abukhalaf, Steve Shenouda, Michayla R. Williams, Rasheeba Nizam, Sumi E. John, Sindhu Jacob, Mohammed Alhusayan, Shibu J. Kurian, Shihab P. Kochumon, Sardar T.A.K. Sindhu, Fawaz Alzaid, Mohamed Abu-Farha, Jehad Abubaker, Alphonse T. Thangavel, Rasheed Ahmad, Fahd AlMullaDr. Ashraf Al Madhoun  Immunology and MicrobiologyVerapamil Increases ß-Cells Proliferation in MIN6 Cells and ß-Cell Mass in Zebrafish ModelPoster
Hossein Arefanian, Fatemah Bahman, Ashraf Al Madhoun, Fawaz Alzaid, Sardar T. Sindhu, Michayla R. Williams, Fatema Alrashed, Rasheeba Nizam, Sindhu Jacob, Sumi E. John, Mohammed Alhusayan, Shibu J. Kurian, Nermeen A. Abukhalaf, Steve Shenouda, Halemah Alsaeed, Shihab P. Kochumon, Mohamed Abu-Farha, Jehad Abubaker, Alphonse T. Thangavel, Rasheed Ahmad, Fahd AlmullaDr. Ashraf Al Madhoun  Immunology and MicrobiologyIncreased Glucose Sensing and Insulin Secretion Induced by Verapamil Is Associated with Enhanced Oxygen Consumption Rate in MIN6 ß-CellsPoster
Hossein Arefanian, Fatemah Bahman, Ashraf Al Madhoun, Sardar T. Sindhu, Fatema Alrashed, Shihab P. Kochumon, Rasheeba Nizam, Sumi E. John, Sindhu Jacob, Mohammed Alhusayan, Nermeen A. Abukhalaf, Steve Shenouda, Halemah Alsaeed, Shibu J. Kurian, Michayla R. Williams, Fawaz Alzaid, Mohamed Abu-Farha, Jehad Abubaker, Alphonse T. Thangavel, Fahd AlmullaDr. Ashraf Al MadhounImmunology and MicrobiologyPretreatment with Verapamil Increases MIN6 Mouse ß-Cell Survival after Exposure to Cytotoxic StressorsPoster
Mohammed Dashti, Naser Ali, Hussain Alsaleh, Rasheeba Nizam, Fahd Al-Mulla, Thangavel Alphonse ThanarajDr. Mohammed DashtiGenetics and BioinformaticsMitochondrial Haplogroup H Is Protective against Type 2 Diabetes in Arabs from Gulf RegionPoster
Jehad Abubaker, Salman Al-Sabah, Irina Al-Khairi, Preethi Cherian, Nermeen Abukhalaf, Hossein Arefanian, Carol Dsouza, Suleiman Al-Sabah, Fahd Al-Mulla, Mohamed Abu-Farha.Dr. Jehad AbubakerBiochemistry and Molecular Biology  Comparable Improvement in NAFLD, Weight Loss, and Lipid Metabolism in Rats Treated with Dual GLP-1–GIP Receptor Agonist (Tirzepatide) and Gastric Sleeve.Oral
Anindya Ghosh, Marc Prentki, Yat Hei Leung, Jeffrey Yu, Robert Sladek, Isabelle Chénier, Abel K. Oppong, Marie-Line Peyot, S.R.Murthy Madiraju, Irina Al-Khairi, Jehad Abubaker, Fahd Al-Mulla, Mohamed Abu-Farha. Anindya GhoshBiochemistry and Molecular BiologyAdipocyte ANGPTL8 regulates insulin sensitivity and thermogenic programing.Oral
Fatheya Alawadi, samir H. Assaad-Kalillf, Wael Almahmeed, Naji Alamuddin, Hessa AlKandari, Jihad Haddad, Lise Lotte N. Husemoen, Rayaz A Malik, Emel Mashaki Ceyhan, Hani Sabbour, Sam Salek, Gputav Yadav, Subodh VermaHessa AlkandariPopulation HealthPrevalence of Atherosclerotic Cardiovascular Diseases in women with Type 2 Diabetes across the Middle East and Africa: Primary Gender analysis of PACT-MEA StudyPoster
Ashraf Al Madhoun, Dania Haddad, Shihab Kochumon, Sardar Sindhu, Reeby Thomas, Lavina Miranda, Fatema Al Rashed, Rasheed Ahmad, Fahd Al Mulla.Ashraf Al MadhounGenetics and Bioinformatics; Immunology and MicrobiologyAdipose Tissue Dectin-1 Upregulation in Hyperglycemic Obesity Involves TNF-α/NF-kBPoster
Siham Abdelgani; Ahmed Khattab; John Adams; Mohamed Abu-Farha; Guisepe Daniele; Fahd Al-Mulla; Stefano Del Prato; Ralph A. DeFronzo; Muhammad Abdul-GhaniSiham AbdelganiTranslational Research / Biochemistry and Molecular BiologyDistinct Mechanisms Responsible for the Increase in Glucose Production and Ketone Formation Caused by Empagliflozin in T2DM PatientsPoster

Figure 4. Breakdown of conferences/events by region.

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