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Our Research Spotlight

Body composition, physical function, physical activity, sleep, and metabolic health in patients with diabetes: a cohort study

At DDI, we are focusing on how lifestyle can impact diabetes through different diet and exercise interventions. The importance of body composition and physical activity for metabolic health is well established, with an emerging importance for muscle function. The main role of muscle is to allow body movements via the generation of force, with the importance of this highlighted in conditions associated with muscle mass loss, such as sarcopenia. In a recent meta-analysis, it was shown that grip strength is negatively associated with type 2 diabetes incidence. The excess risk of cardiovascular disease (CVD) is attenuated in those with high grip strength. In collaboration with the University of Glasgow, we aim to follow a cohort of people with type 1 and type 2 diabetes with detailed phenotyping of body composition, physical function, physical activity, sleep and metabolic health to be able to answer various research questions and compare across cohorts from other countries, such as UK Biobank.

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